:root{
  /* Matched to the White Book treatment already used on Pearl, so the two
     sites read as one system: Arial Narrow in the data zone, a #D9D9D9
     small-caps band over every section, black header rows, and the manual's
     own blue for citations. */
  --paper:#FFFFFF; --card:#FFFFFF; --card-2:#F2F2F2; --band:#D9D9D9;
  --ink:#000000; --ink-2:#1A1A1A; --ink-3:#5A5A5A;
  --rule:#000000; --rule-2:#B4B4B4;
  --accent:#1F6B45; --accent-soft:#E3EEE8; --accent-ink:#175436;
  --warn:#A61B1B; --warn-soft:#F6E2E2;
  --caution:#8A5A12;
  --link:#0432FF;
  --bar:#000000; --bar-track:#D9D9D9;
  --c-acei:#2F5C8F; --c-arb:#1F6B45; --c-bb:#5B4A9E; --c-ccb:#8A5A12; --c-diu:#5C6672;
  --c-nit:#A61B1B; --c-vas:#7A5A2E; --c-alp:#2E6E7A; --c-d1:#7A4A7A; --c-cen:#445466;
  --shadow:none;
  --r:0px;
  color-scheme:light;
  --sans:Arial,"Helvetica Neue",Helvetica,"Liberation Sans",sans-serif;
  --serif:Arial,"Helvetica Neue",Helvetica,"Liberation Sans",sans-serif;
  /* the data zone is condensed, which is how nineteen columns fit at all */
  --narrow:"Arial Narrow",Arial,"Helvetica Neue",Helvetica,"Liberation Sans Narrow",sans-serif;
  --mono:"Arial Narrow",Arial,"Helvetica Neue",Helvetica,"Liberation Sans Narrow",sans-serif;
  /* the one place a condensed face cannot do the job */
  --code:ui-monospace,"SF Mono",Menlo,Consolas,"Liberation Mono",monospace;
}
.pm.caution,.bx.caution{color:#8A5E14}
*{box-sizing:border-box}
body{margin:0;background:var(--paper);color:var(--ink);font-family:var(--sans);
  font-size:15px;line-height:1.55;-webkit-font-smoothing:antialiased}
.wrap{max-width:min(1680px,97vw);margin:0 auto;padding:0 22px 72px}

/* ---------- masthead ---------- */
.mast{padding:38px 0 22px;border-bottom:1px solid var(--rule)}
.eyebrow{font-family:var(--mono);font-size:11px;letter-spacing:.14em;text-transform:uppercase;
  color:var(--ink-3);margin:0 0 10px}
h1{font-family:var(--serif);font-weight:600;font-size:clamp(30px,4.6vw,44px);line-height:1.08;
  margin:0 0 12px;letter-spacing:-.015em;text-wrap:balance}
.dek{margin:0;max-width:74ch;color:var(--ink-2);font-size:16px}
.dek strong{color:var(--ink);font-weight:600}
.provenance{display:flex;flex-wrap:wrap;gap:8px 26px;margin-top:20px;
  font-family:var(--mono);font-size:11.5px;color:var(--ink-3)}
.provenance b{color:var(--ink-2);font-weight:500}

/* ---------- tabs ---------- */
.tabs{display:flex;gap:2px;margin:26px 0 0;border-bottom:1px solid var(--rule);flex-wrap:wrap}
.tab{appearance:none;background:none;border:0;border-bottom:2px solid transparent;
  padding:11px 15px;font:600 13.5px/1 var(--sans);color:var(--ink-3);cursor:pointer;
  letter-spacing:.01em;transition:color .13s}
.tab:hover{color:var(--ink-2)}
.tab[aria-selected="true"]{color:var(--accent-ink);border-bottom-color:var(--accent)}
.tab:focus-visible{outline:2px solid var(--accent);outline-offset:-2px;border-radius:3px 3px 0 0}
.panel[hidden]{display:none}

/* ---------- control rail ---------- */
.rail{position:sticky;top:0;z-index:20;background:var(--paper);
  border-bottom:1px solid var(--rule);padding:8px 0 8px;margin-bottom:14px}
.rail-grid{display:flex;flex-wrap:wrap;gap:8px 18px;align-items:flex-end}
.ctl{display:flex;flex-direction:column;gap:3px;min-width:0}
.ctl > label,.ctl > .lbl{font-family:var(--mono);font-size:10px;letter-spacing:.13em;
  text-transform:uppercase;color:var(--ink-3)}
.ctl input[type=range]{width:120px;accent-color:var(--accent);margin:0;height:20px}
.pair{display:flex;align-items:center;gap:9px}
.pair input[type=number]{width:58px;font-family:var(--mono);font-variant-numeric:tabular-nums;
  text-align:right;padding:4px 6px}
.pair .u{font-family:var(--mono);font-size:11px;color:var(--ink-3)}
/* cost + adverse-effect cells */
.cost{font-family:var(--mono);font-variant-numeric:tabular-nums;white-space:nowrap;text-align:right}
.cost .amt{font-weight:500}
.cost.pricey .amt{color:var(--warn)}
.cost .tier{display:block;font-size:12px;letter-spacing:.07em;color:var(--ink-3);text-transform:uppercase}
.span2{grid-column:1/-1}
/* frequency + formulation marks */
.subtag{display:inline-block;font-family:var(--mono);font-size:12px;letter-spacing:.04em;
  padding:1px 5px;margin-left:6px;border-radius:3px;vertical-align:1px;cursor:help;
  border:1px solid var(--rule);color:var(--ink-2);background:var(--card-2);white-space:nowrap}
.freq{display:inline-block;font-family:var(--mono);font-size:13px;font-weight:600;
  letter-spacing:.05em;padding:0 4px;margin-left:6px;border-radius:3px;
  background:var(--accent-soft);color:var(--accent-ink);vertical-align:1px}
.when{display:inline-block;font-family:var(--mono);font-size:12px;font-weight:600;
  letter-spacing:.05em;padding:0 3px;margin-left:3px;border-radius:3px;
  border:1px solid var(--rule);color:var(--ink-3);vertical-align:1px}
.forms{margin-top:4px;display:flex;flex-wrap:wrap;gap:4px;align-items:baseline}
.formlbl{font-family:var(--mono);font-size:11.5px;letter-spacing:.1em;text-transform:uppercase;
  color:var(--ink-3);margin-right:2px}
.formchip{font-family:var(--mono);font-size:12.5px;color:var(--ink-2);
  border:1px solid var(--rule-2);border-radius:3px;padding:1px 5px;white-space:nowrap}
.formchip b{color:var(--ink-2);font-weight:600}
/* combination guidance */
.guide{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
  box-shadow:var(--shadow);padding:20px 22px;margin:0 0 22px}
.guide h3{margin:0 0 8px;font-family:var(--serif);font-weight:600;font-size:19px;letter-spacing:-.01em}
.guide-lede{margin:0 0 18px;color:var(--ink-2);font-size:14.5px;max-width:74ch}
.guide-lede em{color:var(--ink);font-style:normal;font-weight:600}
.guide-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(255px,1fr));gap:18px 26px}
.gcard h4{margin:0 0 7px;font-family:var(--mono);font-size:10.5px;letter-spacing:.13em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.gcard p{margin:0;font-size:13.5px;color:var(--ink-2);line-height:1.5}
.gcard em{color:var(--ink);font-style:italic}
.glist{margin:0;padding-left:16px;font-size:13.5px;color:var(--ink-2);line-height:1.5}
.glist li{margin-bottom:5px}
.glist b{color:var(--ink)} .glist b.warn{color:var(--warn)}
.gnote{margin:9px 0 0;font-size:12.5px;color:var(--ink-3);line-height:1.5}
.gnote b{color:var(--ink-2)}
.gsub{margin:22px 0 9px;font-family:var(--mono);font-size:10.5px;letter-spacing:.13em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.cmp{border-collapse:collapse;width:100%;min-width:560px;font-size:14px}
.cmp th{text-align:left;font-family:var(--mono);font-size:12.5px;letter-spacing:.11em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500;padding:4px 10px 4px 0;
  border-bottom:1px solid var(--rule)}
.cmp td{padding:5px 10px 5px 0;border-bottom:1px solid var(--rule-2);
  vertical-align:top;color:var(--ink-2)}
.cmp td:first-child{color:var(--ink);font-weight:500;white-space:nowrap}
.cmp td.warn{color:var(--warn);font-weight:500}
.cmp tr:last-child td{border-bottom:0}
.okflag.alt{color:var(--ink-2);background:var(--card-2);border:1px solid var(--rule)}
.aerow{padding:10px 0;border-bottom:1px solid var(--rule-2)}
.aerow:last-of-type{border-bottom:0}
.aehead{display:flex;align-items:center;gap:7px;flex-wrap:wrap;margin-bottom:3px;font-size:14px}
.aehead .mut{font-family:var(--mono);font-size:11.5px}
.aebody{font-size:13px;line-height:1.5;color:var(--ink-2)}
.aebody .imp{color:var(--warn);font-weight:500}
.aenote{font-family:var(--mono);font-size:11px;color:var(--ink-3);margin-top:3px}
.monitorline{margin:12px 0 0;padding-top:11px;border-top:1px solid var(--rule);
  font-size:13px;color:var(--ink-2)}
.monitorline b{color:var(--ink)}
.xtrap.far{color:var(--warn);font-weight:700}
.ae{font-size:16px;line-height:1.25;color:var(--ink-2);max-width:165px;min-width:0}
.ae .imp{color:var(--warn);font-weight:500}
a.cite{display:inline-block;font-family:var(--mono);font-size:11px;letter-spacing:.06em;
  text-transform:uppercase;text-decoration:none;vertical-align:2px;margin-left:4px;
  padding:0 4px;border-radius:3px;border:1px solid var(--rule);
  color:var(--ink-3);background:var(--card-2);white-space:nowrap}
a.cite:hover{border-color:var(--accent);color:var(--accent-ink);background:var(--accent-soft)}
a.cite:focus-visible{outline:2px solid var(--accent);outline-offset:1px}
.difitem{display:block;margin-bottom:3px}
.difitem:last-child{margin-bottom:0}
.aesum{color:var(--ink-2);font-size:13px}
.ci{max-width:none;min-width:108px}
.morechip[hidden],.cond[hidden]{display:none}
.subcol{font-size:15.5px;color:var(--ink-2);white-space:nowrap}
td .cbadge{margin:0}
.cond{display:inline-block;font-size:14px;line-height:1.25;padding:0 4px;margin:0 3px 0 0;
  border-radius:3px;white-space:nowrap;cursor:help;border:1px solid transparent}
.cond.x{background:var(--warn-soft);color:var(--warn);border-color:var(--warn-soft)}
.cond.c{background:var(--card-2);color:#8A5E14;border-color:var(--rule)}
.cond.i{background:var(--accent-soft);color:var(--accent-ink);border-color:var(--accent-soft)}
.condnote{display:block;font-size:12.5px;color:var(--ink-3);margin-top:2px}
.morechip{display:inline-block;font-family:var(--mono);font-size:12.5px;letter-spacing:.03em;
  padding:0 4px;margin-left:2px;border-radius:3px;background:var(--accent-soft);
  color:var(--accent-ink);white-space:nowrap}
.detailgrid{display:grid;grid-template-columns:repeat(auto-fit,minmax(300px,1fr));
  gap:10px 24px;padding-top:6px}
.detailgrid h5{margin:0 0 4px;font-family:var(--mono);font-size:12px;letter-spacing:.11em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.detailgrid .body{font-size:13.5px;color:var(--ink-2);line-height:1.5}
.ae .mon{display:block;font-family:var(--mono);font-size:12.5px;color:var(--ink-3);margin-top:2px}
.xtrap{font-family:var(--mono);font-size:13px;color:var(--ink-3);margin-left:4px;cursor:help}
.readout{font-family:var(--mono);font-size:13px;color:var(--ink);font-weight:500;
  font-variant-numeric:tabular-nums}
.readout .u{color:var(--ink-3);font-weight:400}
select,input[type=search],input[type=number]{font:500 13px/1.3 var(--sans);color:var(--ink);
  background:var(--card);border:1px solid var(--rule);border-radius:var(--r);padding:5px 8px}
select:focus-visible,input:focus-visible,button:focus-visible{outline:2px solid var(--accent);outline-offset:1px}
input[type=search]{min-width:170px}
.seg{display:inline-flex;border:1px solid var(--rule);border-radius:var(--r);overflow:hidden;background:var(--card)}
.seg button{appearance:none;background:none;border:0;padding:5px 10px;cursor:pointer;
  font:500 12.5px/1.3 var(--mono);color:var(--ink-2);border-right:1px solid var(--rule-2)}
.seg button:last-child{border-right:0}
.seg button[aria-pressed="true"]{background:var(--band);color:var(--ink)}
.chips{display:flex;flex-wrap:wrap;gap:6px;align-items:flex-start}
.chip{appearance:none;border:1px solid var(--rule);background:var(--card);color:var(--ink-2);
  border-radius:100px;padding:4px 9px;font:500 12px/1.2 var(--sans);cursor:pointer;
  display:inline-flex;align-items:center;gap:6px;transition:border-color .13s,background .13s}
.chip .dot{width:7px;height:7px;border-radius:100px;background:currentColor;flex:none}
.chip[aria-pressed="true"]{border-color:var(--accent);background:var(--accent-soft);color:var(--accent-ink)}
.toggle{display:inline-flex;align-items:center;gap:7px;font-size:12.5px;color:var(--ink-2);cursor:pointer}
.toggle input{accent-color:var(--accent);width:15px;height:15px;margin:0}
.linkbtn{appearance:none;background:none;border:0;color:var(--accent-ink);font:500 12.5px/1 var(--sans);
  cursor:pointer;text-decoration:underline;text-underline-offset:3px;padding:6px 2px}

/* ---------- table ---------- */
/* The prose column is capped for readability, but a 19-column table is not
   prose: it breaks out of .wrap and takes the viewport, so the flexible text
   columns get the room they need and a sideways scroll is a last resort rather
   than the default on a wide screen. 100svw rather than 100vw so a vertical
   scrollbar cannot push the page sideways. */
.tablewrap{overflow:visible;background:var(--card);border:1px solid var(--rule);
  border-radius:var(--r);box-shadow:var(--shadow);
  margin-inline:calc(50% - 50svw + 10px)}
@supports not (width:100svw){.tablewrap{margin-inline:0}}
table{border-collapse:collapse;width:100%;min-width:0}
/* the rail is sticky too, so the header sticks just below it, never under it */
thead th{position:sticky;top:var(--railH,0px);z-index:2;background:var(--card-2);border-bottom:1px solid var(--rule);
  font-family:var(--mono);font-size:11.5px;letter-spacing:.11em;text-transform:uppercase;
  color:var(--ink-3);text-align:left;padding:7px 7px;font-weight:500;
  white-space:nowrap;line-height:1.25}
thead th.num{text-align:right}
/* A header on one line sets a floor on its column, and nineteen of those floors
   are wider than a laptop. Below the width where the table fits outright, let
   them fold instead - folding a header is a smaller cost than a sideways
   scroll, and above this width nothing folds. */
@media (max-width:1740px){
  thead th,thead th.num{white-space:normal;overflow-wrap:break-word}
}
thead th.sortable{cursor:pointer;user-select:none}
thead th.sortable:hover{color:var(--ink-2)}
thead th .arrow{opacity:.35;margin-left:3px}
thead th[aria-sort] .arrow{opacity:1;color:var(--accent)}
tbody td{border-bottom:1px solid var(--rule-2);padding:5px 7px;vertical-align:middle;
  line-height:1.3}
tbody tr.drugrow{cursor:pointer}
tbody tr.drugrow:hover{background:var(--card-2)}
tbody tr.detail > td{padding:0 7px 7px;border-bottom:1px solid var(--rule-2)}
tbody tr.detail[hidden]{display:none}
.exp{font-family:var(--mono);font-size:12px;color:var(--ink-3);text-align:center;width:26px;
  user-select:none}
tr[aria-expanded="true"] .exp{color:var(--accent-ink)}
tbody tr:last-child td{border-bottom:0}
tbody tr:hover{background:var(--card-2)}
.num{font-family:var(--mono);font-variant-numeric:tabular-nums;text-align:right;white-space:nowrap}
.rank{font-family:var(--mono);font-size:13.5px;color:var(--ink-3);text-align:right;width:30px}
.drug{font-weight:600;letter-spacing:-.005em}
.drug .sub{display:block;font-weight:400;font-size:13px;color:var(--ink-3);font-family:var(--mono);margin-top:0}
.cls-ACEi{color:var(--c-acei)} .cls-ARB{color:var(--c-arb)} .cls-BB{color:var(--c-bb)}
.cls-CCB{color:var(--c-ccb)} .cls-Diuretic{color:var(--c-diu)}
.cls-Nitro{color:var(--c-nit)} .cls-Vasodil{color:var(--c-vas)}
.cls-Alpha{color:var(--c-alp)} .cls-D1{color:var(--c-d1)} .cls-Central{color:var(--c-cen)}
/* class badge: distinct shape AND distinct colour AND a text abbreviation,
   so the class survives greyscale printing and colour-vision deficiency */
.cbadge{display:inline-flex;align-items:center;gap:4px;padding:1px 5px 1px 4px;border-radius:4px;
  border:1px solid currentColor;background:color-mix(in srgb,currentColor 11%,transparent);
  font:600 14px/1.3 var(--mono);letter-spacing:.04em;white-space:nowrap;vertical-align:1px}
.cbadge svg{display:block;flex:none}
.legend{display:flex;flex-wrap:wrap;gap:8px 14px;align-items:center;margin:0 0 12px;
  font-family:var(--mono);font-size:12px;color:var(--ink-3)}
.legend .item{display:inline-flex;align-items:center;gap:6px}
.bigval{font-family:var(--mono);font-size:18px;font-weight:500;font-variant-numeric:tabular-nums}
.pi{font-family:var(--mono);font-size:13px;color:var(--ink-3);white-space:nowrap;font-variant-numeric:tabular-nums}
/* Magnitude ramp for the two mmHg columns (and onset/offset inpatient, where
   there is no mmHg to rank on): seven muted steps, cool to warm - blue, teal,
   green, olive, bronze, rust, brick - so adjacent steps differ in hue and not
   only in darkness, which is what lets 10 and 15 be told apart at a glance,
   without shouting. Every step clears 5:1 on white; weight rises with the
   step as a second channel for greyscale print. */
.r0,.cost .amt.r0,.ipkin.r0{color:#466AAA;font-weight:400}
.r1,.cost .amt.r1,.ipkin.r1{color:#34757F;font-weight:500}
.r2,.cost .amt.r2,.ipkin.r2{color:#317748;font-weight:500}
.r3,.cost .amt.r3,.ipkin.r3{color:#5B742F;font-weight:600}
.r4,.cost .amt.r4,.ipkin.r4{color:#826935;font-weight:600}
.r5,.cost .amt.r5,.ipkin.r5{color:#9C5B40;font-weight:600}
.r6,.cost .amt.r6,.ipkin.r6{color:#AE4747;font-weight:700}
.r1,.kin .kmain.r1,.cost .amt.r1,.ipkin.r1{color:#0E7490;font-weight:500}
.r2,.kin .kmain.r2,.cost .amt.r2,.ipkin.r2{color:#15803D;font-weight:500}
.r3,.kin .kmain.r3,.cost .amt.r3,.ipkin.r3{color:#4D7C0F;font-weight:600}
.r4,.kin .kmain.r4,.cost .amt.r4,.ipkin.r4{color:#B45309;font-weight:600}
.r5,.kin .kmain.r5,.cost .amt.r5,.ipkin.r5{color:#C2410C;font-weight:700}
.r6,.kin .kmain.r6,.cost .amt.r6,.ipkin.r6{color:#B91C1C;font-weight:700}
/* one line per row, in all three tables; the open row is where text wraps */
#drugtable tbody td,#combotable tbody td,#iptable tbody td{white-space:nowrap;overflow:hidden;text-overflow:ellipsis}
#drugtable tbody tr.detail > td,#combotable tbody tr.detail > td,#iptable tbody tr.detail > td{
  white-space:normal;overflow:visible;text-overflow:clip;max-width:none}
/* Every other column shrinks to its content (a 1% width is clamped up to the
   content's own width), and the two chip columns split what is left; their
   max-width:0 keeps their content from pushing the table wider, and the
   150px floor means a narrow window scrolls sideways rather than starving
   them. fitChips() then decides how many chips each cell can show. */
#drugtable tbody td:not(.ci),#combotable tbody td:not(.ci),#iptable tbody td:not(.ci){width:1%}
#drugtable tbody td.ci,#combotable tbody td.ci,#iptable tbody td.ci{max-width:0;width:auto;min-width:150px}
/* a laptop window: a lower floor lets the table fit without a sideways scroll */
@media (max-width:1500px){
  #drugtable tbody td.ci,#combotable tbody td.ci,#iptable tbody td.ci{min-width:120px}
}
#drugtable tbody td.ae{max-width:165px}
#drugtable tbody td.drug{max-width:240px}
#drugtable tbody td.subcol{max-width:120px}
td .freq{margin-left:0}
#combotable tbody td.drug{max-width:330px}
#combotable tbody td.cmarks{white-space:nowrap}
.kin .ksub{display:none}
/* kmain is a block so the sub-line could sit under it; with the sub-line gone
   it has to go back inline or the taper mark drops to a second row */
#drugtable .kin .kmain,#combotable .kin .kmain{display:inline}
.stopcell{white-space:nowrap}
.stopmark{display:inline-block;font-family:var(--narrow);font-size:12.5px;font-weight:700;
  letter-spacing:.03em;text-transform:uppercase;padding:0 4px;border:1px solid currentColor;
  cursor:help}
.stopmark.tap{color:var(--warn)}
.stopmark.ok{color:var(--ink-3)}
.bar{height:7px;background:var(--bar-track);border-radius:100px;overflow:hidden}
.bar > i{display:block;height:100%;background:var(--bar);border-radius:100px}
.band{display:inline-block;font-family:var(--mono);font-size:12.5px;letter-spacing:.08em;
  text-transform:uppercase;padding:3px 7px;border-radius:4px;white-space:nowrap;
  border:1px solid var(--rule);color:var(--ink-2);background:var(--card-2)}
.band.moderate{border-color:var(--accent);color:var(--accent-ink);background:var(--accent-soft)}
.band.high{background:var(--ink);color:var(--paper);border-color:var(--ink)}
.ev{font-family:var(--mono);font-size:15px;color:var(--ink-2);font-variant-numeric:tabular-nums;white-space:nowrap}
.ev.thin{color:var(--warn)}
/* onset / offset: how quickly the drug turns on and off. A dotted underline
   marks a figure that was not measured as a blood-pressure time course but
   inferred from the labelled pharmacokinetics, or carried from the class. */
.kin{line-height:1.25}
.kin .kwrap{display:inline-block;text-align:right}
/* the figure the column sorts on, sized to be read at a glance down the column */
.kin .kmain{display:block;font-size:16.5px;color:var(--ink);font-weight:500}
.kin .ksub{display:block;font-size:12px;color:var(--ink-3);letter-spacing:.01em}
.kin .ksub.mut{color:var(--rule)}
.kin .soft{border-bottom:1px dotted var(--ink-3);cursor:help}
.kin .cl{color:var(--ink-3);border-bottom-color:var(--rule)}
.kin .tap{color:var(--warn);letter-spacing:.07em;text-transform:uppercase;font-size:11.5px;
  font-weight:600}
.note .kin,.note .kin span{display:inline;font-size:inherit}
.note .kin .tap{font-size:12.5px}
.ladder{display:block}
/* the formulation a row prices and doses, where the drug has more than one
   in use; the dashed tag names the single model entry two rows share */
.formtag{display:inline-block;font-family:var(--narrow);font-size:12px;font-weight:700;letter-spacing:.02em;
  padding:0 3px;margin-left:4px;border:1px solid var(--rule-2);color:var(--ink-2);vertical-align:1px;
  white-space:nowrap}
.formtag.shared{border-style:dashed;font-weight:400;color:var(--ink-3);cursor:help}
.nonus{font-family:var(--mono);font-size:12px;letter-spacing:.08em;color:var(--ink-3);
  border:1px dashed var(--rule);border-radius:3px;padding:1px 4px;margin-left:6px;white-space:nowrap}

/* ---------- notes / callouts ---------- */
.note{background:var(--card);border:1px solid var(--rule);border-left:3px solid var(--accent);
  border-radius:var(--r);padding:13px 16px;margin:18px 0;font-size:13.5px;color:var(--ink-2);
  max-width:78ch}
.note.warn{border-left-color:var(--warn)}
.note b{color:var(--ink)}
.count{font-family:var(--mono);font-size:13px;color:var(--ink-3);margin:14px 0 8px}

/* ---------- builder ---------- */
.builder{display:grid;grid-template-columns:minmax(0,1.15fr) minmax(0,.85fr);gap:22px;align-items:start}
@media (max-width:820px){.builder{grid-template-columns:1fr}}
.card{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
  box-shadow:var(--shadow);padding:18px}
.card h2,.card h3{margin:0 0 14px;font-family:var(--serif);font-weight:600;letter-spacing:-.01em}
.card h2{font-size:19px} .card h3{font-size:16px}
.slot{display:grid;grid-template-columns:1fr minmax(210px,.8fr) 32px;gap:8px;align-items:center;margin-bottom:9px}
.slot select{width:100%}
.slot .rm{appearance:none;background:none;border:1px solid var(--rule);border-radius:var(--r);
  color:var(--ink-3);cursor:pointer;font-size:15px;line-height:1;padding:7px 0;width:32px}
.slot .rm:hover{color:var(--warn);border-color:var(--warn)}
.addbtn{appearance:none;background:var(--card-2);border:1px dashed var(--rule);border-radius:var(--r);
  color:var(--ink-2);padding:8px 13px;font:500 13px/1 var(--sans);cursor:pointer;margin-top:4px}
.addbtn:hover{border-color:var(--accent);color:var(--accent-ink)}
.result{display:flex;gap:26px;flex-wrap:wrap;padding:16px 0 4px;border-top:1px solid var(--rule-2);margin-top:16px}
.metric .k{font-family:var(--mono);font-size:10px;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-3)}
.metric .v{font-family:var(--mono);font-size:29px;font-weight:500;line-height:1.15;
  font-variant-numeric:tabular-nums;letter-spacing:-.02em}
.metric .v small{font-size:14px;color:var(--ink-3);font-weight:400}
.flag{display:flex;gap:9px;align-items:flex-start;background:var(--warn-soft);border-radius:var(--r);
  padding:10px 13px;margin-top:11px;font-size:13px;color:var(--ink)}
.flag .ic{color:var(--warn);font-weight:700;flex:none;font-family:var(--mono)}
.flag.info{background:var(--accent-soft)} .flag.info .ic{color:var(--accent-ink)}
.flag.good{background:var(--accent-soft)} .flag.good .ic{color:var(--accent)}
.okflag{display:inline-block;font-family:var(--mono);font-size:12px;letter-spacing:.07em;
  text-transform:uppercase;color:var(--accent-ink);background:var(--accent-soft);
  border-radius:3px;padding:1px 5px;margin-left:7px;white-space:nowrap}
td.num .sub{display:block;font-family:var(--mono);font-size:12.5px;color:var(--ink-3);
  font-weight:400;margin-top:1px}
td.ev .sub{display:block;font-family:var(--mono);font-size:12.5px;color:var(--ink-3);margin-top:1px}
.kv{display:grid;grid-template-columns:auto 1fr;gap:5px 14px;font-size:13px;margin:0}
.kv dt{font-family:var(--mono);font-size:11px;letter-spacing:.09em;text-transform:uppercase;
  color:var(--ink-3);align-self:center}
.kv dd{margin:0;font-family:var(--mono);font-variant-numeric:tabular-nums}

/* ---------- method ---------- */
.prose{max-width:70ch}
.prose h2{font-family:var(--serif);font-weight:600;font-size:21px;margin:30px 0 10px;letter-spacing:-.012em}
.prose h3{font-family:var(--serif);font-weight:600;font-size:16px;margin:22px 0 7px}
.prose p,.prose li{color:var(--ink-2);font-size:14.5px}
.prose strong{color:var(--ink);font-weight:600}
.prose code{font-family:var(--mono);font-size:12.5px;background:var(--card-2);border:1px solid var(--rule-2);
  border-radius:4px;padding:1px 5px;color:var(--ink)}
.eq{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);padding:14px 16px;
  font-family:var(--mono);font-size:13px;color:var(--ink);overflow-x:auto;margin:12px 0;line-height:1.9}
.eq .c{color:var(--ink-3)}
.prose a{color:var(--accent-ink);text-underline-offset:3px}
.stat-row{display:flex;flex-wrap:wrap;gap:10px;margin:14px 0}
.stat{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);padding:10px 14px;min-width:126px}
.stat .k{font-family:var(--mono);font-size:9.5px;letter-spacing:.12em;text-transform:uppercase;color:var(--ink-3)}
.stat .v{font-family:var(--mono);font-size:19px;font-weight:500;font-variant-numeric:tabular-nums}
footer{margin-top:44px;padding-top:18px;border-top:1px solid var(--rule);
  font-size:12.5px;color:var(--ink-3);max-width:78ch}
footer a{color:var(--ink-2)}
.goal-ok{color:var(--accent-ink);font-weight:600}
.fit{display:inline-block;font-family:var(--mono);font-size:9px;font-weight:600;
  letter-spacing:.07em;text-transform:uppercase;padding:1px 5px;margin-left:6px;
  border-radius:3px;vertical-align:1px;cursor:help}
.fit.good{background:var(--ink);color:var(--paper)}
.fit.bad{background:var(--warn-soft);color:var(--warn);border:1px solid var(--warn)}
.classae{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
  margin:0 0 12px;padding:0;box-shadow:var(--shadow)}
.classae summary{cursor:pointer;padding:11px 15px;font-size:13px;color:var(--ink-2);
  list-style:none;font-weight:500}
.classae summary::-webkit-details-marker{display:none}
.classae summary::before{content:'\25B8';display:inline-block;margin-right:8px;
  color:var(--ink-3);transition:transform .15s}
.classae[open] summary::before{transform:rotate(90deg)}
.classae summary:focus-visible{outline:2px solid var(--accent);outline-offset:-2px;border-radius:var(--r)}
#condKeyBody{padding:0 15px 13px;display:grid;
  grid-template-columns:repeat(auto-fit,minmax(300px,1fr));gap:6px 24px}
.ckrow{display:flex;align-items:baseline;gap:8px;flex-wrap:wrap;font-size:12.5px}
.ckrow .cond{flex:none;min-width:104px;text-align:center}
.ckfull{color:var(--ink-2)}
.ckrow .condnote{flex-basis:100%;margin-left:112px;margin-top:0}
#classAeBody{padding:0 15px 13px;display:grid;grid-template-columns:repeat(auto-fit,minmax(280px,1fr));gap:14px 24px}
.cae h4{margin:0 0 4px;font-family:var(--mono);font-size:10px;letter-spacing:.11em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.caebody{font-size:12.5px;line-height:1.5;color:var(--ink-2)}
.caebody .imp{color:var(--warn);font-weight:500}
.aerow.cls{background:var(--card-2);border-radius:var(--r);padding:10px 12px;margin-bottom:8px;border-bottom:0}
.advice{margin-top:14px;padding-top:13px;border-top:1px solid var(--rule)}
.advice h4{margin:0 0 9px;font-family:var(--mono);font-size:10px;letter-spacing:.13em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.adv{display:flex;gap:9px;align-items:flex-start;font-size:13px;line-height:1.5;
  color:var(--ink-2);margin-bottom:7px}
.adv .ic{flex:none;width:16px;font-family:var(--mono);font-weight:700;text-align:center}
.adv b{color:var(--ink)}
.adv.step .ic{color:var(--accent-ink)}
.adv.warn{color:var(--ink)} .adv.warn .ic{color:var(--warn)}
.adv.no .ic{color:var(--warn)}
.adv.dose .ic{color:var(--ink-3)}
.ladderline{padding:10px 0;border-bottom:1px solid var(--rule-2)}
.ladderline:last-child{border-bottom:0}
.lhead{display:flex;align-items:center;gap:7px;flex-wrap:wrap;margin-bottom:7px;font-size:13.5px}
.lrungs{display:flex;align-items:stretch;gap:4px;flex-wrap:wrap}
.larrow{align-self:center;color:var(--ink-3);font-size:11px}
.rung{appearance:none;cursor:pointer;border:1px solid var(--rule);border-radius:var(--r);
  background:var(--card);padding:5px 10px;display:flex;flex-direction:column;gap:1px;
  align-items:center;min-width:66px;transition:border-color .12s,background .12s}
.rung .mg{font-family:var(--mono);font-size:12px;font-weight:600;color:var(--ink);
  font-variant-numeric:tabular-nums}
.rung .dl{font-family:var(--mono);font-size:9.5px;color:var(--ink-3);
  font-variant-numeric:tabular-nums;white-space:nowrap}
.rung.up:hover{border-color:var(--accent);background:var(--accent-soft)}
.rung.up:hover .dl{color:var(--accent-ink)}
.rung.down{opacity:.72}
.rung.down:hover{border-color:var(--rule);background:var(--card-2)}
.rung.cur{border-color:var(--accent);background:var(--accent);cursor:default}
.rung.cur .mg,.rung.cur .dl{color:var(--paper)}
.rung .rf{color:var(--warn);margin-left:2px}
.rung.cur .rf{color:inherit}
.rung:focus-visible{outline:2px solid var(--accent);outline-offset:1px}
.pbanner{background:var(--card);border:1px solid var(--rule);border-left:3px solid var(--accent);
  border-radius:var(--r);padding:11px 15px;margin:0 0 12px;font-size:13px;color:var(--ink-2)}
.pbanner div{margin-bottom:4px} .pbanner div:last-child{margin-bottom:0}
.pbanner b{color:var(--ink)}
.profpanel summary{cursor:pointer;list-style:none;padding:2px 0}
.profpanel summary::-webkit-details-marker{display:none}
.profpanel summary::after{content:' \25BE';color:var(--ink-3);font-size:11px}
.profpanel[open] summary::after{content:' \25B4'}
.profsum{font-size:12px;color:var(--ink-2);margin-left:10px}
.profsum.active{color:var(--accent-ink);font-weight:600}
.profgroups{display:grid;grid-template-columns:repeat(auto-fit,minmax(232px,1fr));
  gap:10px 20px;padding:10px 0 4px}
.profgroup .glabel{font-family:var(--mono);font-size:9px;letter-spacing:.12em;
  text-transform:uppercase;color:var(--ink-3);margin-bottom:5px}
.profgroup .chips{gap:5px}
.chip.prof{gap:0;text-align:left}
.chip.prof .pm{flex:none}
.pm{display:inline-block;font-family:var(--mono);font-size:9px;font-weight:700;
  min-width:11px;text-align:center;margin-right:3px;vertical-align:1px}
.pm.contra{color:var(--warn)}
.pm.caution{color:#8A5E14}
.pm.ind{color:var(--accent-ink)}
.pm.info{color:var(--ink-3)}
.chip.prof[aria-pressed="true"] .pm{color:var(--ink)}
.plab{flex:none;white-space:nowrap}
.proflegend{grid-column:1/-1;font-size:11.5px;color:var(--ink-3);padding-top:8px;
  margin-top:4px;border-top:1px solid var(--rule-2);display:flex;flex-wrap:wrap;gap:4px 16px;
  align-items:center}
.bx.contra{color:var(--warn)}
.bx.caution{color:#8A5E14}
.bx.ind{color:var(--accent-ink)}
.chip.prof[aria-pressed="true"]{background:var(--band);color:var(--ink);border-color:var(--rule)}
.btnrow{display:flex;gap:8px;flex-wrap:wrap;margin-top:14px}
.btnrow .addbtn{margin-top:0}
#nexttable{min-width:720px}
#nexttable td.drug{font-weight:500}
#nextCard .band{font-size:9.5px}
.goal-off{color:var(--warn);font-weight:600}

/* ---------- inpatient ------------------------------------------------------
   A self-contained view. It shares the page's table and chip styles so it
   looks like the rest of the atlas, but none of its data touches the
   outpatient efficacy model: there are no mmHg estimates here, because the
   Wang model has no coefficient for a titrated infusion. ------------------- */
.ip-lede{margin:0 0 16px;color:var(--ink-2);font-size:14.5px}
.ip-lede b{color:var(--ink)}
.defs{display:grid;grid-template-columns:repeat(auto-fit,minmax(288px,1fr));gap:12px;margin:0 0 18px}
.def{background:var(--card);border:1px solid var(--rule);border-left:3px solid var(--rule);
  border-radius:var(--r);padding:12px 15px;box-shadow:var(--shadow)}
.def.crisis{border-left-color:var(--warn)}
.def.marked{border-left-color:#C08A2E}
.def.mild{border-left-color:var(--accent)}
.def h4{margin:0 0 4px;font-family:var(--sans);font-size:13.5px;font-weight:600;color:var(--ink)}
.def .thr{font-family:var(--mono);font-size:12px;color:var(--ink-2);display:block;margin-bottom:5px;
  font-variant-numeric:tabular-nums}
.def p{margin:0;font-size:12.5px;color:var(--ink-3);line-height:1.5}
.def .old{font-family:var(--mono);font-size:10px;letter-spacing:.05em;color:var(--ink-3)}
.eod{background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
  padding:13px 16px;margin:0 0 18px;box-shadow:var(--shadow)}
.eod h4{margin:0 0 9px;font-family:var(--mono);font-size:10px;letter-spacing:.13em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
/* one flowing line, not a grid of blocks - a system w/ one long item was
   taking a whole row to itself */
.eodflow{margin:0 0 6px;font-size:12.5px;line-height:1.6;color:var(--ink-2)}
.eodflow b{font-family:var(--mono);font-size:11px;letter-spacing:.07em;text-transform:uppercase;
  color:var(--ink-3);font-weight:700;margin-right:2px}
.eodflow .sep{color:var(--rule-2);margin:0 6px;font-weight:700}
.eodflow .addmark{color:var(--warn);font-weight:700;font-size:10px;cursor:help}
/* condition-specific targets */
.dz{border-collapse:collapse;width:100%;font-size:14px}
.dz thead th{position:static;background:var(--card-2)}
.dz td{padding:3px 5px;border-bottom:1px solid var(--rule-2);vertical-align:top;
  color:var(--ink-2);line-height:1.38}
.dz tr:last-child td{border-bottom:0}
.dz td.dzname{color:var(--ink);font-weight:600;white-space:nowrap;font-size:14px}
.dz td.dzname .sub{display:block;font-weight:400;font-size:12.5px;color:var(--ink-3);
  font-family:var(--mono);white-space:normal;margin-top:1px}
.dz td.goal{font-family:var(--mono);font-size:13px;color:var(--ink);white-space:nowrap;
  font-variant-numeric:tabular-nums}
.dz td.goal .win{display:block;font-size:12.5px;color:var(--warn);letter-spacing:.06em;
  text-transform:uppercase;margin-top:2px;white-space:nowrap}
.dz td.goal .win.slow{color:var(--ink-3)}
.dz .why{display:block;font-size:12.5px;color:var(--ink-3);margin-top:3px;line-height:1.45}
.dz tr.dzrow{cursor:pointer}
.dz tr.dzrow:hover td{background:var(--card-2)}
.dz tr.dzdetail > td{padding:2px 7px 6px;background:var(--card-2)}
.dz tr.dzdetail[hidden]{display:none}
.dz tr.dzrow .exp{color:var(--ink-3);text-align:center;width:22px}
.dz tr.baserow td{background:var(--card-2)}
.dz tr.baserow td.dzname{font-weight:700}
.dz tr.lastbase td{border-bottom:2px solid var(--rule)}
.dz b{color:var(--ink);font-weight:600}
.dz .why b{color:var(--ink-2)}
.dz .no{color:var(--warn);font-weight:500}
.dz em{font-style:italic;color:var(--ink)}
.dz td.goal{max-width:210px;white-space:normal}
/* provenance mark: on the card, on the card but corrected, or added here */
.src{display:inline-block;font-family:var(--mono);font-size:12px;font-weight:600;letter-spacing:.05em;
  padding:0 4px;border-radius:3px;white-space:nowrap;cursor:help;border:1px solid transparent;
  vertical-align:1px}
.src.wb{background:var(--accent-soft);color:var(--accent-ink);border-color:var(--accent-soft)}
.src.fix{background:#F3E6CC;color:#7A5610;border-color:#E3D0A8}
.src.add{background:var(--card-2);color:var(--ink-3);border-color:var(--rule)}
/* how often you reach for it - the column that stops a floor BP question
   turning into a scroll past phentolamine */
.tier{display:inline-block;font-family:var(--narrow);font-size:12px;font-weight:700;
  letter-spacing:.03em;text-transform:uppercase;padding:0 4px;white-space:nowrap;cursor:help;
  border:1px solid currentColor}
.tier.t1{background:var(--ink);color:var(--paper);border-color:var(--ink)}
.tier.t2{background:none;color:var(--ink-2);border-color:var(--rule-2)}
.tier.t3{background:none;color:var(--warn);border-color:var(--warn)}
.usecell{max-width:120px}
/* a drug named in the prose jumps to its row */
.dlink{border-bottom:1px dashed currentColor;cursor:pointer;color:inherit;text-decoration:none}
.dlink:hover{border-bottom-style:solid;background:var(--band)}
.dlink:focus-visible{outline:2px solid var(--ink);outline-offset:1px}
@keyframes ipflash{0%,55%{background:var(--band)}100%{background:transparent}}
#ipbody tr.flash td{animation:ipflash 1.8s ease-out}
.srckey{display:flex;flex-wrap:wrap;gap:7px 18px;align-items:center;margin:0 0 12px;
  font-family:var(--mono);font-size:12px;color:var(--ink-3)}
.srckey .item{display:inline-flex;align-items:center;gap:6px}
/* dosing: start, titrate, ceiling on their own lines in the open row */
.dose{font-size:14px;line-height:1.45;color:var(--ink-2)}
.dose .d1{display:block;color:var(--ink);font-weight:500}
.dose .d2{display:block;color:var(--ink-3);font-size:12.5px}
.dose .dmax{display:block;font-family:var(--mono);font-size:12px;color:var(--ink-3)}
.dose .dmax b{color:var(--ink-2);font-weight:600}
.dose .was{display:block;font-family:var(--mono);font-size:12.5px;color:#8A5E14;margin-top:2px}
/* how controllable the agent is - the property that decides drip vs push */
.ctrlb{display:inline-block;font-family:var(--mono);font-size:12.5px;letter-spacing:.02em;
  text-transform:uppercase;padding:0 5px;border-radius:4px;white-space:nowrap;cursor:help;
  border:1px solid var(--rule);background:var(--card-2);color:var(--ink-2)}
.ctrlb.t3{background:var(--ink);color:var(--paper);border-color:var(--ink)}
.ctrlb.t2{background:var(--accent-soft);color:var(--accent-ink);border-color:var(--accent-soft)}
.ctrlb.t0{background:var(--warn-soft);color:var(--warn);border-color:var(--warn-soft)}
.route{display:inline-block;font-family:var(--mono);font-size:12.5px;font-weight:600;letter-spacing:.05em;
  padding:0 5px;border-radius:3px;border:1px solid var(--rule);color:var(--ink-2);
  background:var(--card-2);white-space:nowrap}
.route.gtt{border-color:var(--accent);color:var(--accent-ink);background:var(--accent-soft)}
.setting{font-family:var(--mono);color:var(--ink-2);cursor:help}
.routecell{max-width:156px}
.ipkin{font-family:var(--mono);font-size:13px;color:var(--ink);font-variant-numeric:tabular-nums;
  white-space:nowrap;text-align:right}
.ipkin .k2{display:block;font-size:12px;color:var(--ink-3);letter-spacing:.01em}
.ipkin .soft{border-bottom:1px dotted var(--ink-3);cursor:help}
#iptable tbody td.ipnote{max-width:185px}
.ipnote{color:var(--ink-2)}
#iptable tbody td.subcol{max-width:125px}
#iptable tbody td.drug{max-width:200px}
#iptable tbody td.num{max-width:104px}
.ipdetail .glance{grid-column:1/-1}
.ipdetail .glance .body b{margin-right:3px}
.ipdetail .glance .body .difitem .cond{margin-right:4px}
.ipdetail{display:grid;grid-template-columns:repeat(auto-fit,minmax(290px,1fr));gap:10px 24px;
  padding:8px 0 3px}
.ipdetail h5{margin:0 0 4px;font-family:var(--mono);font-size:12px;letter-spacing:.11em;
  text-transform:uppercase;color:var(--ink-3);font-weight:500}
.ipdetail .body{font-size:13.5px;color:var(--ink-2);line-height:1.5}
.ipdetail .body b{color:var(--ink)}
.ipdetail .body .imp{color:var(--warn);font-weight:500}
.fixbox{grid-column:1/-1;background:var(--card-2);border:1px solid var(--rule);border-radius:var(--r);
  padding:9px 12px;font-size:13.5px;color:var(--ink-2);line-height:1.5}
.fixbox h5{margin-bottom:5px}
.fixbox .from{font-family:var(--mono);font-size:12.5px;color:#8A5E14}
.ipsub{margin:30px 0 10px;font-family:var(--serif);font-size:19px;font-weight:600;
  letter-spacing:-.01em;color:var(--ink)}
.ipsub .n{font-family:var(--mono);font-size:11px;font-weight:400;color:var(--ink-3);
  letter-spacing:.06em;margin-left:9px;text-transform:uppercase}
.ipintro{margin:0 0 14px;font-size:13.5px;color:var(--ink-2)}
/* the inpatient notes use the whole width, side by side where two fit */
#panel-inpt .note{max-width:none}
#ipTop .notes{display:grid;grid-template-columns:repeat(auto-fit,minmax(560px,1fr));gap:0 18px;align-items:start}
#ipTop .notes .note{margin:0 0 14px}
#ipTop .eod{margin-bottom:14px}
.ipintro b{color:var(--ink)}

/* ---------- White Book skin ------------------------------------------------
   The MGH housestaff manual is Arial on white: hairline black boxes, a grey
   band behind every header, blue underlined citations, no shadows and no
   rounded corners. Everything below re-dresses the components already on the
   page in that language; nothing here changes what any control does.
   The palette is sampled from the manual - band #D8D8D8, links pure blue,
   the shield teal #107888 and Harvard crimson #B81010 as the only accents.
   Two deliberate departures: the drug-class marks keep distinct hues, because
   nine classes cannot be told apart in one colour, and the equation blocks
   keep a real monospace, because Arial will not align them. ---------------- */
body{font-size:14.5px;line-height:1.45}
table b,table strong,.dz b{font-weight:600}
a{color:var(--link);text-underline-offset:2px}
.prose a{color:var(--link)}

/* the manual's page header: section bold on the left, topic plain on the right */
.mast{padding:26px 0 14px;border-bottom:2px solid var(--rule)}
.eyebrow{text-align:center;font-size:10px;letter-spacing:.1em;color:var(--ink-3);
  margin:0 0 10px;text-transform:none}
h1{display:flex;align-items:baseline;justify-content:space-between;gap:16px 26px;flex-wrap:wrap;
  font-family:var(--sans);font-weight:400;margin:0 0 10px;letter-spacing:-.01em;line-height:1.1}
h1 .sec{font-weight:700;font-size:clamp(22px,3.4vw,31px)}
h1 .topic{font-weight:400;font-size:clamp(18px,2.8vw,28px);text-align:right;flex:1 1 auto}
.dek{font-size:14px;max-width:88ch}
.provenance{gap:6px 22px;margin-top:14px;font-size:11.5px;letter-spacing:0}

/* tabs: the manual has none, so keep the mechanism and mute the styling */
.tabs{border-bottom:1px solid var(--rule);margin-top:18px}
.tab{font:700 11.5px/1 var(--sans);letter-spacing:.07em;text-transform:uppercase;padding:9px 13px}
.tab[aria-selected="true"]{color:var(--ink);border-bottom-color:var(--ink);border-bottom-width:3px}
.tab:hover{color:var(--ink)}

/* every surface is a hairline box */
.tablewrap,.guide,.card,.note,.stat,.classae,.def,.eod,.flag{
  border:1px solid var(--rule);border-radius:0;box-shadow:none;background:var(--card)}
.note{border-left:1px solid var(--rule)}
.note.warn{border-left:3px solid var(--warn)}
.flag{border-radius:0}
.eq{border:1px solid var(--rule);border-radius:0;background:var(--card-2)}
.eq,.eq *{font-family:var(--code)}

/* section headers become the manual's band, set the way Pearl sets it:
   small-caps in the condensed face on a flat #D9D9D9 strip, no border */
.ipsub,.prose h2,.guide h3,.card h2,.card h3{
  background:var(--band);border:0;color:var(--ink);
  font-family:var(--narrow);font-weight:700;font-size:15px;line-height:1.3;
  font-variant:small-caps;letter-spacing:.055em;text-transform:none;
  padding:2px 6px;margin:24px 0 8px;display:flex;align-items:baseline;
  justify-content:space-between;gap:14px;flex-wrap:wrap}
.card h2,.card h3{margin:-18px -18px 14px}
.ipsub .n{font-size:12px;font-weight:400;font-variant:small-caps;letter-spacing:.05em;
  margin:0;color:var(--ink-2);text-transform:none}
.prose h3{font-family:var(--sans);font-weight:700;font-size:14px;text-decoration:underline;
  text-underline-offset:3px;margin:20px 0 6px;color:var(--ink)}
.gsub,.advice h4,.eod h4,.detailgrid h5,.ipdetail h5,.cae h4,.gcard h4,.ctl > label,.ctl > .lbl,
.formlbl{letter-spacing:.09em;font-weight:700;color:var(--ink-3)}

/* tables: full hairline grid with a grey header band */
table,.dz,.cmp{font-family:var(--narrow)}
thead th{background:var(--ink);color:var(--paper);font-weight:700;font-size:13.5px;
  letter-spacing:.01em;text-transform:none;border-bottom:1px solid var(--rule);padding:2px 4px}
thead th .arrow{opacity:.55}
tbody td{padding:1px 2px;font-size:17.5px;line-height:1.2}
thead th.sortable:hover{color:var(--paper);text-decoration:underline}
thead th[aria-sort] .arrow{color:var(--paper);opacity:1}
thead th + th{border-left:1px solid #4A4A4A}
tbody td{border-bottom:1px solid var(--rule-2)}
#drugtable tbody td + td,#combotable tbody td + td,#iptable tbody td + td,
.dz tbody td + td,.cmp td + td{border-left:1px solid var(--rule-2)}
tbody tr:hover,tbody tr.drugrow:hover{background:var(--card-2)}
tbody tr.detail > td{background:var(--card-2);border-left:0}
.dz thead th{background:var(--band);color:var(--ink)}
.rank{color:var(--ink-3)}

/* citations, exactly as the manual sets them: blue, underlined, no chrome */
a.cite{border:0;background:none;border-radius:0;padding:0;margin-left:4px;vertical-align:0;
  font-family:var(--narrow);font-size:12.5px;letter-spacing:0;text-transform:none;
  color:var(--link);text-decoration:underline;text-underline-offset:1.5px}
a.cite:hover,a.cite:focus-visible{background:none;border:0;color:var(--link)}

/* chips and marks: hairline outlines rather than pastel fills */
.cond,.cbadge,.freq,.when,.subtag,.morechip,.okflag,.band,.formchip,.nonus,
.src,.ctrlb,.route,.fit,.chip,.seg,.seg button,.addbtn,.rung,.slot .rm,
select,input[type=search],input[type=number]{border-radius:0}
.cond,.cond.i,.cond.x,.cond.c{border:1px solid currentColor;background:none;padding:1px 5px}
.cond.i{color:var(--accent-ink)} .cond.x{color:var(--warn)} .cond.c{color:var(--caution)}
.freq,.okflag,.morechip{background:var(--band);color:var(--ink);border:1px solid var(--rule-2)}
.band{border:1px solid var(--rule-2);background:none;color:var(--ink-2)}
.band.moderate{background:var(--band);color:var(--ink);border-color:var(--rule-2)}
.band.high{background:var(--ink);color:var(--paper);border-color:var(--ink)}
.bar{border-radius:0;border:1px solid var(--rule-2);height:8px}
.bar > i{border-radius:0;background:var(--bar)}
.src.wb{background:var(--band);color:var(--ink);border-color:var(--rule-2)}
.src.fix{background:none;color:var(--caution);border-color:var(--caution)}
.src.add{background:none;color:var(--ink-3);border-color:var(--rule-2)}
.ctrlb.t3{background:var(--ink);color:var(--paper);border-color:var(--ink)}
.ctrlb.t2{background:var(--band);color:var(--ink);border-color:var(--rule-2)}
.ctrlb.t1{background:none;color:var(--ink-2);border-color:var(--rule-2)}
.ctrlb.t0{background:none;color:var(--warn);border-color:var(--warn)}
.route.gtt{background:var(--band);color:var(--ink);border-color:var(--rule)}
.dose .was,.fixbox .from{color:var(--caution)}
.fixbox{background:var(--paper);border-color:var(--rule)}
.def{border-left-width:4px}
.def.crisis{border-left-color:var(--warn)}
.def.marked{border-left-color:var(--caution)}
.def.mild{border-left-color:var(--accent)}
.def h4{font-size:14px}
.def .old{text-transform:none;letter-spacing:0}

/* controls */
.seg button[aria-pressed="true"]{background:var(--band);color:var(--ink);font-weight:700}
.chip[aria-pressed="true"]{background:var(--band);border-color:var(--rule);color:var(--ink);
  font-weight:700}
.chip{border-radius:0;font-weight:400}
.linkbtn{color:var(--link)}
.rung.cur{background:var(--ink);border-color:var(--ink)}
.rung.cur .mg,.rung.cur .dl{color:var(--paper)}
.rung.up:hover{border-color:var(--ink);background:var(--band)}
.rung.up:hover .dl{color:var(--ink)}
.metric .v{font-family:var(--sans);font-variant-numeric:tabular-nums}
.stat .v,.readout,.kv dd,.num,.cost,.pi,.ev,.ipkin,.rank,.dz td.goal{
  font-variant-numeric:tabular-nums}
.flag.info,.flag.good{background:var(--band)}
.flag.info .ic,.flag.good .ic{color:var(--ink)}
.classae summary{font-weight:700}
#classAeBody,#condKeyBody{border-top:1px solid var(--rule-2);padding-top:11px}


/* ---------- phone: the wide tables become stacked cards ---------- */
@media (max-width:720px){
  .wrap{padding:0 14px 56px}
  .rail{position:static}
  .ctl input[type=range]{width:120px}
  .tablewrap{border:0;background:none;box-shadow:none;overflow-x:visible;margin-inline:0}
  #drugtable,#combotable{min-width:0;width:100%}
  #drugtable thead,#combotable thead{position:absolute;width:1px;height:1px;
    overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}
  #drugtable tbody tr,#combotable tbody tr{display:grid;
    grid-template-columns:auto 1fr;gap:2px 10px;
    background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
    padding:11px 13px;margin-bottom:10px;box-shadow:var(--shadow)}
  #drugtable tbody td,#combotable tbody td{border:0;padding:1px 0;text-align:left}
  #drugtable tbody td.rank,#combotable tbody td.rank{grid-column:1;grid-row:1;
    align-self:center;width:auto;padding-right:4px}
  #drugtable tbody td.drug,#combotable tbody td.drug{grid-column:2;grid-row:1;font-size:15px}
  /* label the value cells, since the header row is gone */
  #drugtable tbody td.num,#drugtable tbody td.cost,#drugtable tbody td.ev,
  #drugtable tbody td.kin,
  #combotable tbody td.num,#combotable tbody td.cost,#combotable tbody td.ev{
    grid-column:1/-1;display:flex;justify-content:space-between;align-items:baseline;
    gap:12px;padding:3px 0;border-top:1px solid var(--rule-2)}
  /* on a card the two figures sit side by side, label to the left */
  #drugtable tbody td.kin .kmain,#drugtable tbody td.kin .ksub{display:inline}
  #drugtable tbody td.kin .ksub{margin-left:8px}
  #drugtable tbody td::before,#combotable tbody td::before{
    content:attr(data-l);font-family:var(--mono);font-size:12.5px;letter-spacing:.1em;
    text-transform:uppercase;color:var(--ink-3)}
  #drugtable tbody td.drug::before,#combotable tbody td.drug::before,
  #drugtable tbody td.rank::before,#combotable tbody td.rank::before,
  #drugtable tbody td.barcell::before,#combotable tbody td.barcell::before,
  #drugtable tbody td.ae::before{content:none}
  #drugtable tbody td.barcell,#combotable tbody td.barcell{grid-column:1/-1;width:auto;padding:5px 0 2px}
  #drugtable tbody td.ae{grid-column:1/-1;max-width:none;min-width:0;
    padding-top:7px;border-top:1px solid var(--rule-2)}
  #drugtable tbody td.pi{grid-column:1/-1;display:flex;justify-content:space-between;gap:12px}
  #drugtable tbody td:last-child,#combotable tbody td:last-child{grid-column:1/-1;padding-top:6px}
  td.num .sub,td.ev .sub{display:inline;margin-left:6px}
  .cost .tier{display:inline;margin-left:6px}
  .builder{grid-template-columns:1fr}
  #drugtable tbody td.exp{display:none}
  #drugtable tbody tr.detail>td{grid-column:1/-1}
  #drugtable tbody tr.detail{display:block;padding:0 13px 11px;margin:-10px 0 10px;border-radius:0 0 var(--r) var(--r)}
  #drugtable tbody tr.detail[hidden]{display:none}
  .guide{padding:16px}
  .slot{grid-template-columns:1fr 1fr 32px}
  /* the one-line rule is a desktop-table rule; as cards these must wrap again */
  #drugtable tbody td,#combotable tbody td{white-space:normal;overflow:visible;text-overflow:clip;
    max-width:none}
  #drugtable .kin .kmain,#combotable .kin .kmain{display:inline}
  /* the inpatient tables get the same card treatment */
  #iptable,.dz,.triage{min-width:0;width:100%}
  #iptable thead{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0)}
  #iptable tbody tr{display:grid;grid-template-columns:auto 1fr;gap:2px 10px;
    background:var(--card);border:1px solid var(--rule);border-radius:var(--r);
    padding:11px 13px;margin-bottom:10px;box-shadow:var(--shadow)}
  #iptable tbody td{border:0;padding:1px 0;text-align:left}
  #iptable tbody td.rank{grid-column:1;grid-row:1;align-self:center;width:auto;padding-right:4px}
  #iptable tbody td.drug{grid-column:2;grid-row:1;font-size:15px}
  #iptable tbody td[data-l]{grid-column:1/-1;display:flex;justify-content:space-between;
    align-items:baseline;gap:12px;padding:3px 0;border-top:1px solid var(--rule-2)}
  #iptable tbody td[data-l]::before{content:attr(data-l);font-family:var(--mono);font-size:12.5px;
    letter-spacing:.1em;text-transform:uppercase;color:var(--ink-3);flex:none}
  #iptable tbody td[data-l="Indications"],#iptable tbody td[data-l="Avoid in"],
  #iptable tbody td[data-l="Watch"]{display:block}
  #iptable .usecell{max-width:none}
  #iptable tbody td[data-l="Indications"]::before,#iptable tbody td[data-l="Avoid in"]::before,
  #iptable tbody td[data-l="Watch"]::before{display:block;margin-bottom:2px}
  #iptable tbody td.exp{display:none}
  #iptable .dose,#iptable .ipnote{max-width:none}
  #iptable tbody td{white-space:normal;overflow:visible;text-overflow:clip;max-width:none}
  /* the desktop shrink rule carries a :not(.ci), so this has to match its specificity */
  #drugtable tbody td:not(.ci),#drugtable tbody td.ci,#combotable tbody td:not(.ci),#combotable tbody td.ci,
  #iptable tbody td:not(.ci),#iptable tbody td.ci{width:auto;max-width:none;min-width:0}
  #iptable .ipkin{text-align:left}
  #iptable .ipkin .k2{display:inline;margin-left:8px}
  #iptable tbody tr.detail{display:block;padding:0 13px 11px;margin:-10px 0 10px;
    border-radius:0 0 var(--r) var(--r)}
  #iptable tbody tr.detail[hidden]{display:none}
  #iptable tbody tr.detail>td{grid-column:1/-1}
  .dz thead{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0)}
  .dz tbody tr{display:block;background:var(--card);border:1px solid var(--rule);
    border-radius:var(--r);padding:11px 13px;margin-bottom:10px;box-shadow:var(--shadow)}
  .dz tbody td{display:block;border:0;padding:2px 0}
  /* as a card the whole default row tints, not its cells */
  .dz tbody tr.baserow{background:var(--card-2);border-width:2px}
  .dz tbody tr.baserow td,.dz tbody tr.lastbase td{background:none;border-bottom:0}
  .dz td.goal{white-space:normal}
  .defs{grid-template-columns:1fr}
}

@media (prefers-reduced-motion:reduce){*{transition:none!important;animation:none!important}}